|
KMID : 0043319990220030309
|
|
Archives of Pharmacal Research
1999 Volume.22 No. 3 p.309 ~ p.312
|
|
|
Inhibition of Aromatase Activity by Flavonoids
|
|
Jeong Hyeh-Jean
Pezzuto John-M.
Shin Young-Geun
Kim Il-Hyuk
|
|
|
Abstract
|
|
|
|
In searching for potent cancer chemopreventive agents from synthetic or natural products, 28 randomly selected flavonoids were screened for inhibitory effects against partially purified aromatase prepared form human placenta. Over 50% of the flavonoids significantly inhibited aromatase activity, with greatest activity being demonstrated with apigenin , chrysin , and hesperetin .
|
|
|
KEYWORD
|
|
|
Aromatase inhibition, Flavonoids, Breast cancer
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|